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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CHAT
All Species:
5.45
Human Site:
S594
Identified Species:
10
UniProt:
P28329
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P28329
NP_066266.3
748
82536
S594
H
K
A
A
V
P
A
S
E
K
L
L
L
L
K
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001109211
626
70697
T488
A
M
D
D
S
S
V
T
G
H
Q
K
V
E
L
Dog
Lupus familis
XP_543902
686
76910
Y548
A
I
R
A
Q
T
E
Y
T
V
M
A
I
T
G
Cat
Felis silvestris
Mouse
Mus musculus
Q03059
641
71834
Y503
A
I
Q
A
Q
T
E
Y
T
V
M
A
I
T
G
Rat
Rattus norvegicus
P32738
640
71845
Y502
A
M
Q
A
H
K
Q
Y
T
V
M
A
I
T
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509108
643
72737
Y505
A
I
R
A
Q
T
E
Y
T
I
L
A
I
T
G
Chicken
Gallus gallus
Q90YJ9
640
72605
Y502
A
I
A
A
Q
T
N
Y
T
I
L
A
I
T
G
Frog
Xenopus laevis
Q7ZXE1
659
74538
N521
C
S
E
A
L
V
M
N
P
S
K
H
S
P
A
Zebra Danio
Brachydanio rerio
B2ZGJ1
637
71821
L499
A
Q
T
N
Y
T
I
L
A
I
T
G
M
A
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P07668
721
81310
L570
G
E
G
A
N
V
P
L
E
S
D
R
E
D
E
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P32756
627
71299
K489
M
A
S
K
K
E
S
K
E
R
K
L
E
L
F
Sea Urchin
Strong. purpuratus
XP_001185550
675
75787
R537
E
E
K
K
F
L
M
R
E
A
I
K
A
Q
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32796
670
77223
A532
Q
N
G
D
V
P
I
A
E
K
I
Q
A
L
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
37.8
77.9
N.A.
74.7
74.7
N.A.
68.4
66
24
57
N.A.
37.5
N.A.
29.2
46.3
Protein Similarity:
100
N.A.
55.7
82.4
N.A.
79.1
79
N.A.
76.5
74
40.6
68.8
N.A.
56.1
N.A.
45.1
62.4
P-Site Identity:
100
N.A.
0
6.6
N.A.
6.6
6.6
N.A.
13.3
20
6.6
0
N.A.
13.3
N.A.
20
6.6
P-Site Similarity:
100
N.A.
13.3
20
N.A.
20
20
N.A.
20
26.6
20
13.3
N.A.
26.6
N.A.
40
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
27
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
44.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
40
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
53.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
54
8
16
62
0
0
8
8
8
8
0
39
16
8
8
% A
% Cys:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
16
0
0
0
0
0
0
8
0
0
8
0
% D
% Glu:
8
16
8
0
0
8
24
0
39
0
0
0
16
8
8
% E
% Phe:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
8
% F
% Gly:
8
0
16
0
0
0
0
0
8
0
0
8
0
0
39
% G
% His:
8
0
0
0
8
0
0
0
0
8
0
8
0
0
0
% H
% Ile:
0
31
0
0
0
0
16
0
0
24
16
0
39
0
8
% I
% Lys:
0
8
8
16
8
8
0
8
0
16
16
16
0
0
16
% K
% Leu:
0
0
0
0
8
8
0
16
0
0
24
16
8
24
8
% L
% Met:
8
16
0
0
0
0
16
0
0
0
24
0
8
0
0
% M
% Asn:
0
8
0
8
8
0
8
8
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
16
8
0
8
0
0
0
0
8
0
% P
% Gln:
8
8
16
0
31
0
8
0
0
0
8
8
0
8
0
% Q
% Arg:
0
0
16
0
0
0
0
8
0
8
0
8
0
0
0
% R
% Ser:
0
8
8
0
8
8
8
8
0
16
0
0
8
0
0
% S
% Thr:
0
0
8
0
0
39
0
8
39
0
8
0
0
39
8
% T
% Val:
0
0
0
0
16
16
8
0
0
24
0
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
8
0
0
39
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _